Sure. Security filters filter out records that should not reach the user's device. Please evaluate whether you are looking for security filters or merely disabling actions for certain users.
If you are looking for enabling actions only for certain users , you could use condition setting of the action pane in a manner such as
IN (USEREMAIL(), LIST( abc@testaction.com, def@testaction.com, ghk@testaction.com))
where abc@testaction.com, def@testaction.com, ghk@testaction.com are emails of users who should have action enabled.
Relevant articles
Security filters: The Essentials - AppSheet Help
Actions: The Essentials - AppSheet Help
Edit: Made minor changr to the suggseted expression.
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